Drug intelligence / Profile preview

4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid

Development stage
Unknown
Modality
Small Molecules
01

Overview

4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid is a synthetic small molecule belonging to the class of phenylpyridines and naphthyridine derivatives. It has a molecular formula of C21H13N3O4 and a molecular weight of approximately 371.35 g/mol[1][2][5]. The compound features a naphthyridine ring system substituted with a nitrophenyl group and benzoic acid moiety[4]. It is classified as an experimental compound with no approved medical indications or known clinical use as of June 2025[1]. There are no reported clinical trials or patents for this molecule[1]. Its mechanism of action is not established in the literature; however, related naphthyridine derivatives have been studied for potential activity against phosphodiesterase enzymes (PDEs), but there is no direct evidence that this specific compound acts on any particular target.

Other names
4-(8-(3-nitrophenyl)-1,7-naphthyridin-6-yl)benzoic acidBenzoic acid, 4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]-
02

Targets

PDE4APDE4B (3',5'-cyclic-AMP phosphodiesterase 4B)PDE4D (Phosphodiesterase 4D)

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